In bone modeling, which cells are responsible for building new bone in response to bending?

In bone modeling, which cells are responsible for building new bone in response to bending?

• A. Osteoblasts
• B. Osteoclasts
• C. Osteocytes
• D. Chondrocytes

Answer: (A)

Osteoblasts are the builders of new bone. When bone experiences bending, mechanical strain is detected by the bone’s resident cells and signals osteoblasts to lay down new bone matrix and mineralize it in the targeted areas, strengthening the bone where strain occurs. Osteoclasts resorb bone, so they’re not responsible for forming new tissue. Osteocytes act as mechanosensors and orchestrate the response, but they don’t directly create new bone. Chondrocytes form cartilage, not bone, so they aren’t the builders in this scenario.

Osteoblasts are the builders of new bone. When bone experiences bending, mechanical strain is detected by the bone’s resident cells and signals osteoblasts to lay down new bone matrix and mineralize it in the targeted areas, strengthening the bone where strain occurs. Osteoclasts resorb bone, so they’re not responsible for forming new tissue. Osteocytes act as mechanosensors and orchestrate the response, but they don’t directly create new bone. Chondrocytes form cartilage, not bone, so they aren’t the builders in this scenario.